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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8722 | IKIX1 | Antifungal | |
iKIX1 is an Pdr1-dependent gene activation. It re-sensitizes drug-resistant C. glabrata to azole antifungals in vitro and in animal models for disseminated and urinary tract C. glabrata infection. | |||
T2305 | Isavuconazole | BAL-4815,RO-0094815 | P450 , Antibiotic , Antifungal |
Isavuconazole (RO-0094815)(BAL-4815; RO-0094815) is the active component of the new azole antifungal agent BAL8557 with MIC(50)s/MIC(90)s ranged from 0.002/0.004 mg/liter for C. albicans to 0.25/0.5 mg/liter for C. glabr... | |||
T36434 | Sordarin sodium | ||
Sordarin is an inhibitor of fungal protein synthesis originally isolated from S. araneosa.[1] It binds to elongation factor 2 (EF-2) in the presence of ribosomes and inhibits the uncoupled GTPase activity of equimolar mi... | |||
T36437 | Sphinganine (d17:0) | Sphinganine (d17:0) | |
Sphinganine is a synthetic bioactive sphingolipid that inhibits the growth of C. glabrata and C. albicans with a minimum fungicidal concentration (MFC) value of 0.5 μg/ml for both. More commonly, sphinganine is used as a... | |||
T35902 | Milbemycin A4 oxime | ||
Milbemycin A4 oxime is a derivative of milbemycin A4 and a component of milbemycin oxime , compounds that both have insecticidal and nematocidal activity. Milbemycin A4 oxime (0.05 mg/kg) reduces the number of microfilar... | |||
T79384 | Antifungal agent 72 | ||
Antifungal agent 72 (Compound B8) demonstrates potent activity by inhibiting the efflux pump function and downregulating resistance-associated genes via disruption of the Pdr1-KIX interaction (K i : 11.7 μM). It exhibits... | |||
T60965 | Anticandidal agent-1 | ||
Anticandidal agent-1 (compound c2) is a potent and broad-spectrum anticandidal agent that inhibits biofilm through blocking hyphal elongation and filamentation. Anticandidal agent-1 exhibits anticandidal activity against... | |||
T36057 | Diallyl Tetrasulfide | ICD-1585 | |
Diallyl tetrasulfide is an organosulfur compound that has been found in A. sativum and has diverse biological activities, including antimicrobial, antioxidant, and anticancer properties.[1],[2],[3],[4] It is active again... |